Nicotinamide riboside (NR) Increases NADP

In the first controlled clinical trial of nicotinamide riboside (NR), a newly discovered form of Vitamin B3, researchers have shown that the compound is safe for humans and increases levels of a cell metabolite that is critical for cellular energy production and protection against stress and DNA damage. Studies in mice have shown that boosting the levels of this cell metabolite—known as NAD —can produce multiple health benefits, including resistance to weight gain, improved control of bl...

 Creating Online Fictions of Ourselves

The most effective young Facebook users, however—the ones who will probably be winners if Facebook turns out to be a model of the future they will inhabit as adults—are the ones who create successful online fictions about themselves. They tend their doppelgängers fastidiously. They must manage offhand remarks and track candid snapshots at parties as carefully as a politician. Insincerity is rewarded, while sincerity creates a lifelong taint. Certainly, some version of this principle exi...

 A Classic Example of Selective Reporting

One of the classic examples of selective reporting concerns the testing of acupuncture in different countries. While acupuncture is widely accepted as a medical treatment in various Asian countries, its use is much more contested in the West. These cultural differences have profoundly influenced the results of clinical trials. Between 1966 and 1995, there were forty-seven studies of acupuncture in China, Taiwan, and Japan, and every single trial concluded that acupuncture was an effective tre...

 Publication Bias Produces a "Decline Effect"

Jennions, similarly, argues that the decline effect is largely a product of publication bias, or the tendency of scientists and scientific journals to prefer positive data over null results, which is what happens when no effect is found. The bias was first identified by the statistician Theodore Sterling, in 1959, after he noticed that ninety-seven per cent of all published psychological studies with statistically significant data found the effect they were looking for. A “significant” re...